Esperion reports positive results in late-stage trial of heart disease treatment

Esperion Therapeutics Inc. announced positive results Wednesday from a late-stage trial of a treatment for atherosclerotic cardiovascular disease, a condition involving a build-up of sticky cholesterol-rich plaque that can cause heart attack or stroke. Esperion said the phase 3 trial of bempedoic acid for patients with elevated low density lipoprotein cholesterol (LDL-C) met its primary endpoint of LDL-C lowering. “Patients treated with bempedoic acid also achieved a significantly greater reduction of 33 percent in high-sensitivity C-reactive protein (hsCRP), an important marker of the underlying inflammation associated with cardiovascular disease, compared to the placebo group which had an increase of two percent (p

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