Fortress Bio soars after reporting breakthrough with CAR-T cancer approach

Fortress Biotech Inc. gained as much as 75% in late trading Wednesday after the company detailed a success story for an approach to cancer that has suffered of late. Fortress said a 50-year-old man suffering from a recurrent and particularly deadly form of brain cancer was treated with a drug developed from his own genetically modified T cells in an early clinical trial of the approach, developed by Fortress’s Mustang Bio Inc. unit. The man, who had not responded to previous standard treatments, achieved complete remission and “returned to normal life and work activities,” Fortress Bio said in Wednesday’s news release. The drug, referred to as MB-101, is a form of CAR-T immunotherapy, which uses the patient’s own immunities to fight cancer cells; the approach has generated a lot of buzz, but has been damaged by the deaths of patients in a study by Juno Therapeutics Inc. earlier this year. “This clinical experience provides remarkable evidence of the potential of CAR T cell immunotherapy to improve the treatment of patients with aggressive brain tumors,” said Dr. Christine Brown, lead author of the case study, which will be published in the Dec. 29 edition of the New England Journal of Medicine. Fortress stock moved as high as $4 in late trading after closing at $2.29.

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From:: Stock Market News

API sees 4.2 million barrel rise in U.S. oil inventories: reports

The American Petroleum Institute on Wednesday reported that U.S. crude oil inventories rose 4.2 million barrels in the latest week, news reports said. Official inventory data from the Energy Information Administration is due Thursday morning. Analysts surveyed by The Wall Street Journal expect that report to show a 1.4 million barrel decline in crude supplies.

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From:: Stock Market News

AppDynamics files for an initial public offering

Software company AppDynamics filed for an initial public offering Wednesday, after delaying it earlier this year. The company had previously said it was delaying its offering until 2017 due to uncertainty after the U.S. presidential election, according to the Wall Street Journal. The company filed for an offering of up to $100 million. The company is valued by private investors at $1.9 billion. AppDynamics applied to list on the Nasdaq Global Select under the symbol “AAPD.” The lead underwriters on the offering are Morgan Stanley, Goldman, Sachs & Co. and J.P. Morgan.

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From:: Stock Market News

Stocks end lower; Dow drive for 20,000 thwarted again

Stocks gave up early gains, ending broadly lower and near session lows Wednesday with losses led by the tech sector. The Dow industrials came within 20 points of the psychologically important 20,000 milestone in early trade but soon lost steam. The blue-chip gauge ended the day down 111.36 points, or 0.6%, to end at 19,833.68, according to preliminary figures. The S&P 500 declined 0.8% to 2,249.92. The Nasdaq Composite lost 48.89 points, or 0.9%, to settle at 5,438.56 a day after closing at a record.

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From:: Stock Market News

Market Feels Effects of Rising Rates, Pending Home Sales Pull Back

By Susanne Dwyer

The housing market is feeling the effects of rising mortgage rates, with pending home sales pulling back to year-lows last month as homebuyers struggled to put purchases in play, according to the National Association of REALTORS® (NAR). NAR’s Pending Home Sales Index (PHSI), a forward-looking indicator based on contract signings, dipped 2.5 percent to 107.3 in November, down from 110.0 in October.

“The budget of many prospective buyers last month was dealt an abrupt hit by the quick ascension of rates immediately after the election,” says Lawrence Yun, NAR chief economist. “Already faced with climbing home prices and minimal listings in the affordable price range, fewer home shoppers in most of the country were successfully able to sign a contract.”

All is not lost, however. Rising mortgage rates, according to Yun, will be balanced by a more robust growth in wages in the next year.

“Healthy local job markets amidst tight supply means many areas will remain competitive with prices on the rise,” says Yun. “Those rushing to lock in a rate before they advance even higher will probably have few listings to choose from. Some buyers will have to expand the area of their home search or be forced to delay in order to save a little more money for their down payment.”

The Northeast saw the most pending home sales activity in November, with the PHSI up 0.6 percent to 97.5—now 5.7 percent above one year ago. In the Midwest, the Index was down 2.5 percent to 103.5, 2.4 percent below one year ago. Pending home sales in the South were down 1.2 percent to 118.7, 1.3 percent below one year ago. The Index in the West was down 6.7 percent to 101.0, 1.0 percent below one year ago.

Existing-home sales are still expected to close out 2016 at 5.42 million, which will eclipse 2015 (5.25 million) as the highest since 2006 (6.48 million), according to NAR. The national median existing-home price is also still expected to end 2016 at a 5 percent growth rate.

Looking ahead, existing-home sales are expected to come in at 5.52 million in 2017, while the national median existing-home price is expected to grow 4 percent.

For more information, please visit www.nar.realtor.

For the latest real estate news and trends, bookmark RISMedia.com.

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From:: Finance and Economy

Market Feels Effects of Rising Rates, Pending Home Sales Pull Back

By Susanne Dwyer

The housing market is feeling the effects of rising mortgage rates, with pending home sales pulling back to year-lows last month as homebuyers struggled to put purchases in play, according to the National Association of REALTORS® (NAR). NAR’s Pending Home Sales Index (PHSI), a forward-looking indicator based on contract signings, dipped 2.5 percent to 107.3 in November, down from 110.0 in October.

“The budget of many prospective buyers last month was dealt an abrupt hit by the quick ascension of rates immediately after the election,” says Lawrence Yun, NAR chief economist. “Already faced with climbing home prices and minimal listings in the affordable price range, fewer home shoppers in most of the country were successfully able to sign a contract.”

All is not lost, however. Rising mortgage rates, according to Yun, will be balanced by a more robust growth in wages in the next year.

“Healthy local job markets amidst tight supply means many areas will remain competitive with prices on the rise,” says Yun. “Those rushing to lock in a rate before they advance even higher will probably have few listings to choose from. Some buyers will have to expand the area of their home search or be forced to delay in order to save a little more money for their down payment.”

The Northeast saw the most pending home sales activity in November, with the PHSI up 0.6 percent to 97.5—now 5.7 percent above one year ago. In the Midwest, the Index was down 2.5 percent to 103.5, 2.4 percent below one year ago. Pending home sales in the South were down 1.2 percent to 118.7, 1.3 percent below one year ago. The Index in the West was down 6.7 percent to 101.0, 1.0 percent below one year ago.

Existing-home sales are still expected to close out 2016 at 5.42 million, which will eclipse 2015 (5.25 million) as the highest since 2006 (6.48 million), according to NAR. The national median existing-home price is also still expected to end 2016 at a 5 percent growth rate.

Looking ahead, existing-home sales are expected to come in at 5.52 million in 2017, while the national median existing-home price is expected to grow 4 percent.

For more information, please visit www.nar.realtor.

For the latest real estate news and trends, bookmark RISMedia.com.

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From:: Real Estate News

Home Sales Rocket to Second Highest Point Since 2008

By Susanne Dwyer

In November, sales of new homes hit their second highest peak since 2008, according to data released by the U.S. Census Bureau and the Department of Housing and Urban Development (HUD). While these numbers have been fickle month-to-month, this is a hopeful sign of a surge in demand for the new year to come.

November’s new single-family house numbers came in at a seasonally adjusted annual rate of 592,000. This number is 5.2 percent above the October rate, and 16.5 percent above November 2015’s numbers, which landed at an estimated 508,000.

The average sales price for new homes sold in November was $359,900, while the median sales price was $305,400. This is higher than October’s median price of $302,700, but lower than the $317,000 median recorded in November 2015. At the end of the month, the seasonally adjusted estimate of new houses for sale reached 250,000, a supply of over 5 months if the current sale rate remains.

Source: U.S. Census Bureau

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From:: Finance and Economy

United Shore lands on DOJ hit list, will pay $48m for FHA lending violations

United Shore Financial Services will pay $48 million to settle allegations brought by the Department of Justice, which accused United Shore of violating the False Claims Act by “knowingly originating and underwriting” mortgages that did not meet Federal Housing Administration standards, the DOJ announced Wednesday. The settlement makes United Shore just the latest in a long line of mortgage lenders that settled with the DOJ over alleged FHA lending violations. Click the headline to read more. …read more

From:: Real Estate Wire

Mortgage Complaints Down From Year Ago

Despite a year-over-year increase in average monthly financial services complaints, there was a decrease in mortgage complaints.

For all of November 2016, U.S. consumers filed 23,134 complaints against companies that provide all types of financial services.

That was 14 percent fewer complaints than a month earlier. It was also less than the 21,002 complaints reported for a year earlier.


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From:: Financing